ABSTRACT
Pilomatrixoma is an uncommon adnexal tumor with heterogeneous features can mimic various malignancies and contributes to false positive diagnosis on cytology. It is an uncommon, slow growing, benign skin adnexal neoplasm of hair matrix origin initially described by Malherbe and Chenantais. This tumor is predominantly found in the head and neck region, and presents as a small, asymptomatic, slow-growing dermal, subcutaneous, solitary lesion. More than 50% of these tumors are known to occur in the second decade of life and is often misdiagnosed clinically. Cytological features pose a diagnostic challenge although the histological features are very well delineated. This paper presents the cytological features in two cases outlining the importance of the clinicopathological features that need to be considered for an accurate diagnosis. Awareness of its varied cytologic features and clinical presentation can avoid misdiagnosis.
Subject(s)
Adult , Humans , Male , Neoplasms, Adnexal and Skin Appendage/cytology , Neoplasms, Adnexal and Skin Appendage/diagnosis , Neoplasms, Adnexal and Skin Appendage/pathology , Pilomatrixoma/cytology , Pilomatrixoma/diagnosis , Skin/pathology , Skin Neoplasms/cytology , Skin Neoplasms/diagnosis , Skin Neoplasms/pathologySubject(s)
Biopsy , Cytomegalovirus Infections/complications , Cytomegalovirus Infections/diagnosis , Cytomegalovirus Infections/pathology , Esophagitis/complications , Esophagitis/diagnosis , Esophagitis/pathology , Esophagus/pathology , Histocytochemistry , Humans , Immunocompromised Host , Male , Microscopy , Middle Aged , Necrosis/pathologyABSTRACT
Epithelioid sarcoma is an uncommon slow-growing soft tissue malignancy, associated with a high incidence of local recurrence and metastasis. We report a 26-year-old male with epithelioid sarcoma on the right palm with a long history of over seven years, which was initially misdiagnosed as cutaneous tuberculosis and epithelioid hemangioendothelioma, as a result of which the treatment was delayed. No metastasis was found in our patient. The patient was referred to the oncology centre where he underwent wide excision of the lesion followed by radiotherapy. The review of the literature including clinical and histological differential diagnosis is presented as it mimics inflammatory, benign tumors as well as other malignant conditions.
Subject(s)
Adult , Dermis/pathology , Diagnosis, Differential , Epidermis/pathology , Hand , Hemangioendothelioma, Epithelioid/pathology , Humans , Male , Sarcoma/blood supply , Soft Tissue Neoplasms/blood supplyABSTRACT
Vulvar intraepithelial neoplasia is a precancerous lesion of the vulva, which has been referred to in the past with varied terminology. It can be associated with multicentricity of other neoplastic squamous lesions in the cervix and vagina. We report a case of vaginal intraepithelial neoplasia and concomitant cervical intraepithelial neoplasia in a 30 year old female. An attempt is made to put forth the recent terminology of vulvar intraepithelial neoplasia.